Intramolecular hydrogen bonds in 1,4-dihydropyridine derivatives
نویسندگان
چکیده
منابع مشابه
Intramolecular C-H···O hydrogen bonding in 1,4-dihydropyridine derivatives.
The diastereotopy of the methylene protons at positions 2 and 6 in 1,4-dihydropiridine derivatives with various substituents has been investigated. NMR spectroscopy and quantum chemistry calculations show that the CH···O intramolecular hydrogen bond is one of the factors amplifying the chemical shift differences in the 1H-NMR spectra.
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ژورنال
عنوان ژورنال: Royal Society Open Science
سال: 2018
ISSN: 2054-5703
DOI: 10.1098/rsos.180088